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Everolimus Treatment and Selective Artery Embolization Application in a Case of Tuberous Sclerosis-Related Bilateral Renal Angiomyolipoma
Ismail Emre Ergin1, Aydemir Asdemir1, Abuzer Ozturk1, Esat Korgali1
1Department of Urology, Sivas Cumhuriyet University Faculty of Medicine, Sivas, Türkiye
DOI : 10.5505/GJU.2023.58065
Angiomyolipomas are the most common benign mesenchymal tumors of the kidney. Although
they are often seen sporadically, they can also be observed as a part of the tuberous sclerosis
complex (TSC). They occur at an earlier age in cases associated with tuberous sclerosis (TS),
bilateral mass and epithelioid formation. There are various treatment approaches such as active
surveillance, nephron-sparing surgery, nephrectomy, angioembolization, and use of
mammalian target of rapamycin (mTor) inhibitors. Our case was a patient with bilateral
multiple renal angiomyolipomas associated with TS. We applied mTOR inhibitor and
angioembolization therapy to this patient. In our article, we tried to evaluate our success rate in
our treatment and the treatment regimens to be applied in these patients.
Keywords : angiomyolipoma, tuberous sclerosis, everolimus
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