Grand Journal of Urology
E-ISSN : 2757-7163

Functional Urology
Original Article
Grand J Urol 2025;0(0):, DOI: Fibromiyaljide Psikiyatrik Eşlik Eden Hastalık ve Aşırı Aktif Mesane: Kesitsel Çalışma
Objective: To evaluate the prevalence of overactive bladder (OAB) in women with fibromyalgia (FM) presenting with lower urinary tract symptoms, and to examine the relationship between psychiatric comorbidities and symptom severity in this population. Materials and Methods: This cross-sectional study included 240 women aged 18–65 years who met the 2016 American College of Rheumatology criteria for FM and reported lower urinary tract symptoms for at least three months. OAB was diagnosed based on International Continence Society criteria using the OAB-V8 questionnaire (cut-off ≥8) and a three-day bladder diary. Psychiatric symptoms were assessed using the Hospital Anxiety and Depression Scale (HADS). FM severity was measured using the Widespread Pain Index (WPI), Symptom Severity Scale (SSS), and General Symptom Score (GSS). Patients were divided into FM+OAB and FM−OAB groups. Statistical comparisons and correlation analyses were performed. Results: OAB was identified in 148 of 240 FM patients (61.7%). The FM+OAB group had significantly higher mean age (47.2 ± 7.4 vs. 41.5 ± 10.1 years, p < 0.001) and fibromyalgia diagnosis time (10.5 ± 8.7 vs. 6.3 ± 6.0 years, p < 0.001) compared to the FM−OAB group. Clinically significant anxiety and depression (HADS ≥8) were more prevalent in the FM+OAB group (52.1% vs. 27.3%, p = 0.006). FM+OAB patients also had higher scores for WPI, SSS, and GSS (all p < 0.001). HADS scores correlated positively with FM symptom severity and OAB-V8 scores (ρ = 0.30–0.42, p < 0.01). Conclusion: Overactive bladder is highly prevalent among women with fibromyalgia and is associated with greater psychiatric burden and symptom severity. These findings suggest a shared underlying mechanism driven by central sensitization and emotional dysregulation. Routine screening for OAB and psychological distress in FM patients may enhance diagnostic accuracy and guide comprehensive, multidisciplinary treatment strategies.
Objective: In our study, we aimed to examine the effects of body mass index (BMI) and multiple drug use on urinary incontinence (UI) in diabetic geriatric patients. Materials and Methods: Our study included 246 type 2 diabetes mellitus patients aged 65 and over who applied to our outpatient clinic between October and December 2019 and remained after the exclusion criteria were applied. The relationship between the frequency of UI and age, diabetes age, HbA1c, BMI, number of drugs and gender was investigated. UI described as any involuntary incontinence complaint. The questionnaire contained socio-demographic questions and the International Consultation on Incontinence Modular Questionnaire Urinary Incontinence Short Form (ICIQ-UI SF).with UI were women. Diabetes age and HbA1c level did not differ significantly between those with and without UI. There was a statistically significant relationship between BMI and the number of drugs used with the indication of UI (Mann-Whitney U; p
Objective: To evaluate the pain characteristics of women with overactive bladder (OAB) for investigating the role of central sensitization in OAB pathophysiology. Materials and Methods: Women with OAB over the age of 18 years and healthy volunteers made up the participants in the current study. Pain intensity and quality were analysed with the Short Form of the McGill Pain Questionnaire (SF-MPQ). The Self-Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) was used to assess the presence of neuropathic pain. Pain threshold was evaluated with algometer. The Pressure Pain Threshold measurement was determined as the primary outcome measure of the present study. The Overactive Bladder Awareness Tool (OAB-V8), short forms of the Incontinence Impact Questionnaire-7 (IIQ-7) and Urogenital Distress Inventory-6 (UDI-6) were used to evaluate OAB symptoms. Nottingham Health Profile (NHP) questionnaire was used to reveal quality of life and general health status. Results: According to algometric measurements, OAB patients had lower pain thresholds in 19 anatomical points (p
Objective: To reveal the effect of preoperative Kegel exercises on early period continence rates after open radical prostatectomy. Materials and Methods: Data of patients with open radical prostatectomy between January 2019 and July 2022, in a tertiary academic health center were retrospectively reviewed. Patient" characteristics, perioperative parameters and postoperative follow-up results were recorded. Patients were divided into two groups as those who did Kegel exercises in the preoperative period and those who did not, and groups were compared. Results: There were 38 patients in the Kegel exercise group and 40 patients in the other group. Postoperative 1st month and postoperative 3rd month incontinence rates were similar between the groups (p=0.406, and p=0.387). At 6th months postoperatively, the rate of incontinence in the Kegel group was 7.9%, while it was 25.0% in the other group (p=0.043). Similarly, the rate of incontinence at 1st year postoperatively was significantly lower in the Kegel group (5.3% vs 20.0%, p=0.001). At 6 months postoperatively, the QoL score in the Kegel positive group was 86, while it was 65 in the other group (p=0.001). In the postoperative 1st year controls, the quality of life (QoL) score was statistically significantly higher in patients with preoperative Kegel exercise (p=0.001). Conclusion: Our study demonstrated that preoperative Kegel exercises had a significant positive effect on continence rate after radical prostatectomy in the postoperative 6th month and in the first year follow-up, and preparative Kegel exercises were significantly associated with higher quality of life scores at 6th months and 1st year follow-up.
Grand J Urol 2021;1(3):122-127, DOI: 10.5222/GJU.2021.10820
Objective: We aimed to investigate the efficacy of silodosin in patients with lower urinary tract symptoms (LUTS) caused by benign prostatic hyperplasia (BPH) refractory to previous α-adrenergic receptor (AR) blocker therapy. Materials and Methods: Patients who did not benefit from alpha-blocker therapy but avoided surgical treatment constitute the population of our study. Seventy-five patients were studied in each group; Group 1 was given 8 mg of silodosin, while Group 2 continued the previous alpha-blocker treatment. Results: The initial mean international prostate symptom score (IPSS) was calculated as 20.81±0.97 in Group 1, in the third month there was a decrease of 17.12±1.25 (p
Review Article
Overactive bladder is a serious condition that can significantly impair quality of life. Antimuscarinic agents are recommended as second-line therapy in patients who do not benefit from behavioral therapy. However, the therapeutic efficacy of antimuscarinic agents is limited. Alternative treatment methods to medical treatment have been developed due to its limited effectiveness and frequent side effects. Posterior tibial nerve stimulation (PTNS), transcutaneous tibial nerve stimulation (TTNS), sacral neuromodulation (SNM), intravesical Botulinum toxin-A (BoNT/A) are prominent among these minimally invasive treatment methods in refractory OAB. All these methods have been demonstrated to be effective in the literature. BoNT/A and SNM are more effective, but have been reported to cause more side effects. In refractory OAB, any of these methods can be applied by considering the medical condition and request of the patient.
Case Report
Inguinal bladder herniation is seen in 1% -4% of all inguinal hernia cases; most of them are asymptomatic and come up with swelling in the groin. In symptomatic cases, nonspecific findings such as lower urinary tract symptoms or pain due to strangulation of the hernia sac are seen. Two-stage micturition (manual pressure to the scrotum to empty residual urine) is a pathognomonic sign for the advanced case. Vesicoureteral reflux (VUR), bilateral hydronephrosis, urinary tract infection, acute kidney failure and bladder wall necrosis are complications that may be seen if the problem is not appropriately managed. Preoperative diagnosis rates are low (