Materials and Methods: Between January 2015 and July 2021, patients who underwent OSP and LSP were retrospectively screened. The patients" demographic, preoperative, perioperative, and postoperative data were noted and compared.

Results: The data of a total of 90 patients, including 55 (61.1%) cases in the OSP and 35 cases (38.9%) in the LSP group were analyzed. Age, comorbidity rates, and body mass index scores of the patients were comparable. There was also no significant difference in the preoperatively calculated mean prostate volume, and Qmax of the cases. The mean operative time was significantly longer for LSP (p<0.0001). The median blood loss was 368 cc (250) and 80 cc (35) in the OSP and LSP groups, respectively, indicating significantly higher values in the OSP group (p<0.0001). The mean hospital stay was statistically significantly higher in the OSP group (8.1 ± 4.3 days) compared to the LSP group (3.6 ± 1 days) (p<0.0001). Minor complications were observed in 21 (38.2%) patients in the OSP and five (14.2%) patients in the LSP group with a significant intergroup difference (p=0.007).

Conclusion: Laparoscopic technique is a safe and effective procedure for large prostatic adenomas. Compared to open surgery, LSP has a longer operative time but is associated with greater patient comfort and lower complication rates.