Grand Journal of Urology
E-ISSN : 2757-7163

A Rare Prostate Pathology: Mantle Cell Lymphoma: A Case Report and Literature Review
Selman Unal1, Halil Uzundal1, Turker Soydas1, Asim Ozayar1, Arslan Ardicoglu1, Aydan Kilicarslan2
1Department of Urology, Ankara Yildirim Beyazit University Faculty of Medicine, Ankara, Turkey
2Department of Pathology, Ankara Yildirim Beyazit University Faculty of Medicine, Ankara, Turkey
DOI : 10.5222/GJU.2021.22931
Pages : 142-145
Primary or secondary lymphoma of the prostate is a rare condition. Mantle cell lymphoma (MCL) represent 4-9% of all lymphomas. Prostate involvement with MCL is very rare, with only 11 reported cases up to now. Here we present a case with lower urinary tract symptoms and prostate-specific antigen (PSA) elevation diagnosed with MCL of the prostate. Prostate biopsy was performed in a 70-year-old patient due to increased PSA. After the pathology result was reported as prostatic MCL, imaging studies and sampling of additional pathological specimens were performed for staging. An improvement was observed in the urinary system complaints of the patient who started chemotherapy regimen. While prostatectomy was performed in some of the prostatic MCL cases reported previously, in some, no additional treatment was required after chemotherapy. Our case is the only prostatic MCL case with elevated PSA levels, but did not receive the diagnosis of prostate cancer. Physicians should keep in mind that, prostatic MCL can present with nonspecific symptoms. Staging should be performed in patients whose histopathologic diagnosis is lymphoma of the prostate so as to determine appropriate treatment options.
Keywords : mantle cell lymphoma, prostate, lymphoma, biopsy, diagnosis
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