Grand Journal of Urology
E-ISSN : 2757-7163

Complication Rates and Postoperative Renal Function in Partial Nephrectomy- Which Factors Should be Considered?
Huseyin Cihan Demirel1, Emre Tokuc2, Semih Turk1, Abdullah Hizir Yavuzsan1, Sedat Cakmak3, Sinan Levent Kirecci1, Kaya Horasanli1
1Department of Urology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey
2Department of Urology, University of Health Sciences, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey
3Department of Urology, University of Health Sciences, Istanbul Haseki Training and Research Hospital, Istanbul, Turkey
DOI : 10.5222/GJU.2021.40085
Pages : 101-108
Objective: To specify the prognostic factors predicting complication rates and postoperative renal function in patients operated with partial nephrectomy.

Materials and Methods: Our health center"s archive system was scanned retrospectively for the time interval between January 2006- January 2021 for patients operated with partial nephrectomy for renal mass. History, comorbidities and laboratory results, operational information, tumor morphologies in radiographic images and its specified scores (R.E.N.A.L. score, PADUA score, C-index), peroperative and postoperative complications and pathology results of 148 regularly followed-up patients were analyzed.

Results: Mean age of the patients was 55.04±10.91 years, ratio of male to female was 1.27 and mean tumor size was 3.56 cm. Mean follow-up period was 55.53±42.26 months. Postoperative creatinine value in the 6th month showed an increase of 0.18 mg/dl compared to preoperative value. Estimated glomerular filtration rate (eGFR) also decreased by an average of 18.3%. Operation of grade 4 tumors significantly affected the postoperative renal function. PADUA score (p=0.023) had a significant effect on postoperative GFRs and duration of ischemia. Also, difference in pre-and postoperative GFRs and its percentage change were significantly affected by C-index (p=0.035, p=0.042). Pathological size (p=0.038), R.E.N.A.L. score (p=0.001), PADUA score (p<0.001), duration of ischemia (p=0.045) had a positively and C-index (p=0.001) had a negatively significant correlation with Modified Clavien-Dindo Complication Scoring System.

Conclusion: All nephrometry scores, duration of ischemia and tumor size were associated with the complication rates according to Clavien classification. Tumor grade, PADUA score and C-index are valuable parameters for predicting renal dysfunction after partial nephrectomy.

Keywords : nephrometry score, R.E.N.A.L. score, PADUA score, C-index, nephrectomy, renal function
Viewed : 269
Downloaded : 92