Materials and Methods: Fifty-one patients who underwent MRI before application of MRI fusion biyopsies were included 63,57±8,5 (45-88) years) in this study, On midsagittal T2- weighted MR images, the thickness of subcutaneous and periprostatic fat was calculated as the vertical distance from the pubic symphysis both to the skin and to the prostate, respectively.

Results: The mean (±SD) subcutaneous fat thickness (SCFT) and periprostatic fat thickness (PPFT) were 17.38±13.02 mm and 5.64±3.89 mm, respectively. A positive correlation was found between Gleason scores and PPFT (p<0.001), SCFT (p<0.001), body mass indices (BMIs) (p<0.001), prostate spesific antigen values (PSA) (p=0.002), PSA density (p<0.001). In multivariate analysis, only PPFT was found to be statistically significant in predicting GS ≥7 (p=0.005). It has been shown that the risk of detecting GS ≥7 prostate cancer increases 8.9 times with one mm increase in PPFT values.

Conclusion: Periprostatic fat tissue thickness can be used as an independent predictive factor in foreseeing prostate cancer aggressiveness before application of biopsy or radical prostatectomy.