2023, Vol 3, Issue 1 - Grand Journal of Urology

Current Issue

Editorial (1) Original Article (5) Case Report (2) Authors Index

Editorial

Editorial, Online First: 20 January 2023

Assoc. Prof. Ekrem GUNER

Dear colleagues, I am honored to share with you the first issue of 2023 (volume 3, issue 1) of the Grand Journal of Urology (Grand J Urol) with the contributions of many respected researchers and authors. Grand Journal of Urology (GJU) aims to carry written and visual scientific urology studies to academic platforms and to make significant contributions to the science of urology. Our journal has been abstracted/indexed in EBSCOhost, J-Gate, Index Copernicus International, EuroPub, SciLit, ResearchGate, ScienceGate and Google Scholar international databases. As of these achievements, the Grand Journal of Urology (GJU) has taken its place among the journals indexed by international databases. In this issue of our journal, there are many valuable articles under the subheadings of Urological Oncology, Neurourology, Urolithiasis and General Urology. I hope that these carefully prepared articles will make important contributions to valuable readers, researchers and the urology literature. On this occasion, I would like to express my heartfelt gratitude to our authors who have contributed to our journal with their articles, to our reviewers who have meticulously evaluate the articles. Respectfully yours January 2023 Assoc. Prof. Ekrem GUNER, MD Editor-in-Chief

Original Article

Urological Oncology, Online First: 07 December 2022

Grand J Urol 2023;3(1):001-007, DOI: 10.5505/GJU.2022.09719

Does the Apical Dissection Technique Affect the Oncological and Functional Outcomes in Robot-assisted Laparoscopic Radical Prostatectomy? Collar Technique vs Standard Technique

Ali Unsal, Serhat Cetin, Fazil Polat, Suleyman Yesil, Murat Yavuz Koparal, Ender Cem Bulut, Ali Atan

Objective: To compare the oncological and functional results of the collar technique (CT) with the standard technique (ST) used for the apical dissection in robot-assisted laparoscopic radical prostatectomy (RALP). Materials and Methods: Sixty-five patients were operated using ST, and 61 patients with CT. The oncological and functional results of the two techniques were compared. Results: The continence rates at 1st and 6th months after catheter removal were 59.0% and 90.2% in the CT, and 36.9% and 87.6% in the ST groups, respectively (p=0.02, and p=0.78). There was no significant difference between the two groups in terms of detection rates of surgical margin positivity (p=0.54). In multivariable logistic regression analysis only the choice of the surgical technique was found to be statistically significantly correlated with the continence rate at the first month after the catheter removal (p=0.023). Conclusion: The CT is a surgical technique, which can be used safely in the Robot-Assisted Laparoscopic Prostatectomy (RALP) procedure, with relatively higher early-term continence rates and oncologic outcomes comparable to the standard technique.

Urological Oncology, Online First: 26 December 2022

Grand J Urol 2023;3(1):008-013, DOI: 10.5505/GJU.2022.03522

Correlation of Periprostatic Fat Thickness Measured on Multiparametric MRI with Prostate Cancer Aggressiveness

Dogukan Sokmen, Bedriye Koyuncu Sokmen

Objective : In this study, the relationship between periprostatic and subcutaneous fat thickness on MRI (magnetic resonans imaging) and Gleason scores (GS) was retrospectively evaluated. Materials and Methods: Fifty-one patients who underwent MRI before application of MRI fusion biyopsies were included 63,57±8,5 (45-88) years) in this study, On midsagittal T2- weighted MR images, the thickness of subcutaneous and periprostatic fat was calculated as the vertical distance from the pubic symphysis both to the skin and to the prostate, respectively. Results: The mean (±SD) subcutaneous fat thickness (SCFT) and periprostatic fat thickness (PPFT) were 17.38±13.02 mm and 5.64±3.89 mm, respectively. A positive correlation was found between Gleason scores and PPFT (p

Urological Oncology, Online First: 30 December 2022

Grand J Urol 2023;3(1):014-018, DOI: 10.5505/GJU.2022.52297

Evaluation of Hematological Parameters in Testicular Tumors

Ismail Evren, Yusuf Arikan, Deniz Noyan Ozlu, Mithat Eksi

Objective: Recently, many hematological parameters have been frequently investigated as prognostic and predictive biomarkers for malignancies and inflammatory conditions, with the primary examples of these parameters being neutrophil-lymphocyte ratio (NLR), lymphocytemonocyte ratio (LMR), platelet-lymphocyte ratio (PLR), and mean platelet volume (MPV). In this study, we aimed to investigate the relationship between hematological parameters and prognosis in patients with a diagnosis of testicular malignancy (TM) by evaluating them in comparison with patients that underwent varicocelectomy as a control group. Materials and Methods: A total of 187 patients that underwent radical inguinal orchiectomy due to the diagnosis of testicular tumor were included in Group 1and 128 patients of similar age that underwent varicocelectomy using a similar incision in Group 2 as controls. Hematological and biochemical blood results were collected one day before radical orchiectomy. The parameters of NLR (neutrophil/ lymphocyte counts), PLR (neutrophil/ lymphocyte counts), PLR (platelet/ lymphocyte counts), and LMR (lymphocyte/ monocyte counts) were expressed as the ratios of indicated blood cell components. Following standard inguinal radical orchiectomy, T staging was performed based on the final histology samples, and clinical N and M staging using imaging modalities. Results: The mean (± SD) ages of the patients were 26.5±7.1, and 25.1±8.1 years for Groups 1 and 2, respectively. The neutrophil counts, NLR, and PLR were significantly higher in Group 1, while the lymphocyte count, MPV, and LMR were significantly higher in Group 2 (pT1 stage TM (pT1 in terms of MPV and PLR. Conclusion: We determined NLR and LMR as parameters that can be used in the pathological staging of cases with TM. We consider that these hematological parameters have an important place in predicting the prognosis in this patient group.

Neurourology, Online First: 13 January 2023

Grand J Urol 2023;3(1):019-025, DOI: 10.5505/GJU.2023.73644

Long-Term Effects of Percutaneous Tibial Nerve Stimulation Treatment for Neurogenic Overactive Bladder Due to Multiple Sclerosis: 24-Month Results

Mehmet Sevim, Sibel Canbaz Kabay, Bekir Aras, Sahin Kabay

Objective: In this study, it was aimed to determine the effectiveness of percutaneous tibial nerve stimulation (PTNS) treatment in neurogenic overactive bladder (NOAB) due to multiple sclerosis (MS) by extending the application interval for 24 months from the beginning. Materials and Methods: Patients completed the PTNS treatment with tapering protocols applied for 6, 9, 12, and 24 months. After 12 weeks of therapy, PTNS was applied at 14 day intervals for 3, at 21 day intervals for 3, and at 28 day intervals for 3 months. The patients completed a 3-day voiding diary at the 3rd, 6th, 9th, 12th, and 24th months. The patients were requested to complete validated questionnaires (ICIQ-SF, OAB-V8, OAB-q SF) within 3-month intervals thereafter during their enrolment in the study. Results: The mean age of 57 patients who completed the PTNS treatment protocol and were included in the study was 42.6 ± 8.2 (23-64) years. Fifteen (26.3%) patients were male and 42 (73.6%) were female. The improvements for all voiding diary parameters were significant at 3rd, 6th, 9th, 12th, and 24th months when compared with the baseline. After 24 months, the daily frequencies of voiding decreased by 6.7 (p

Urological Oncology, Online First: 18 January 2023

Grand J Urol 2023;3(1):026-030, DOI: 10.5505/GJU.2023.74745

Can Neutrophil-Lymphocyte Ratio Be Used to Predict Recurrence and Progression in Non-Muscle Invasive Bladder Cancer?

Mammadbaghir Aghasiyev, Cemil Kutsal

Objective: In this study, we aimed to investigate the predictive value of neutrophil-lymphocyte ratio (NLR) in determining progression and recurrence in non-muscle invasive bladder tumors (NMIBC). Materials and Methods: The files of patients who underwent transurethral bladder tumor resection (TUR-BT) in our urology clinic between 2015 and 2020 were reviewed retrospectively. A total of 405 patients were included in the study. The patients were evaluated, and grouped in terms of disease progression, and recurrence observed during follow-up. Elevation of T stage of the disease, low grade tumor progressing to a high grade, and carcinoma in situ (CIS) negative cases advancing into CIS-positive stage were considered as evidence of disease progression. Results: Fifty female, and 355 male patients were included in the study. The mean age of the study population was 64.9 ± 12.75 years. Disease recurrence was detected in 134, and disease progression in 136 out of 405 patients. The mean NLR value of the patients with relapse was 2.45 ± 2.75 (p=0.009). The mean NLRs of patients with, and without progression were 1.94 ± 1.67, and 2.04 ± 2.3, respectively (p=0.645). Conclusion: High NLR value can predict recurrence in the follow-up of NMIBC patients. The preoperatively detected higher NLR value is a warning for the physician and draws attention to the need for more invasive and regular follow-up of the patient.