Acute Proximal Tubular Necrosis Due to Cidofovir Usage in BK Virus Related Hemorrhagic Cystitis in an Allogeneic Stem Cell Transplanted Patient

Sebnem Izmir Guner

doi:10.5222/GJU.2021.25743

Sebnem Izmir Guner¹, Mustafa Teoman Yanmaz², Ekrem Guner³, Pinar Seymen⁴, Melike Nalbant Moray⁵, Isin Kilicaslan⁵

¹Department of Hematology, Istanbul Gelisim University, Memorial Sisli Hospital Hematology and Bone Marrow Transplantation Center, Istanbul, Turkey
²Department of Medical Oncology, Arel University, Memorial Bahcelievler Hospital, Istanbul, Turkey
³Department of Urology, University of Health Sciences, Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey
⁴Department of Nephrology, Halic University, Medicana Kadikoy Hospital, Istanbul, Turkey
⁵Deparment of Pathology, Istanbul University, Faculty of Medicin, Istanbul, Turkey

DOI : 10.5222/GJU.2021.25743

Pages : 71-74

Hemorrhagic cystitis (HS) is a frequently seen complication of bone marrow transplantation. This condition occurs depending on the preparatory regimen of bone marrow transplantation. The BK virus (BKV), a human polyomavirus, is a small double helix DNA virüs belonging to the Papovaviridae family. It is commonly found in societies as an occult infection. Whereas, cidofovir (CDV), an acyclic nucleoside phosphonate, is used as a proven antiviral agent against polyomaviruses. In this case report, acute proximal tubular necrosis due to cidofovir used in hemorrhagic cystitis caused by BK virus, and its treatment in a patient diagnosed with T-lymphoblastic lymphoma in remission, and underwent allogeneic stem cell transplantation, was presented.

Keywords : hemorrhagic cystitis, BK virus, T-lymphoblastic lymphoma, acute proximal tubular necrosis

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Acute Proximal Tubular Necrosis Due to Cidofovir Usage in BK Virus Related Hemorrhagic Cystitis in an Allogeneic Stem Cell Transplanted Patient by Sebnem Izmir Guner is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.