Grand Journal of Urology
E-ISSN : 2757-7163

Acute Proximal Tubular Necrosis Due to Cidofovir Usage in BK Virus Related Hemorrhagic Cystitis in an Allogeneic Stem Cell Transplanted Patient
Sebnem Izmir Guner1, Mustafa Teoman Yanmaz2, Ekrem Guner3, Pinar Seymen4, Melike Nalbant Moray5, Isin Kilicaslan5
1Department of Hematology, Istanbul Gelisim University, Memorial Sisli Hospital Hematology and Bone Marrow Transplantation Center, Istanbul, Turkey
2Department of Medical Oncology, Arel University, Memorial Bahcelievler Hospital, Istanbul, Turkey
3Department of Urology, University of Health Sciences, Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey
4Department of Nephrology, Halic University, Medicana Kadikoy Hospital, Istanbul, Turkey
5Deparment of Pathology, Istanbul University, Faculty of Medicin, Istanbul, Turkey
DOI : 10.5222/GJU.2021.25743
Pages : 71-74
Hemorrhagic cystitis (HS) is a frequently seen complication of bone marrow transplantation. This condition occurs depending on the preparatory regimen of bone marrow transplantation. The BK virus (BKV), a human polyomavirus, is a small double helix DNA virüs belonging to the Papovaviridae family. It is commonly found in societies as an occult infection. Whereas, cidofovir (CDV), an acyclic nucleoside phosphonate, is used as a proven antiviral agent against polyomaviruses. In this case report, acute proximal tubular necrosis due to cidofovir used in hemorrhagic cystitis caused by BK virus, and its treatment in a patient diagnosed with T-lymphoblastic lymphoma in remission, and underwent allogeneic stem cell transplantation, was presented.
Keywords : hemorrhagic cystitis, BK virus, T-lymphoblastic lymphoma, acute proximal tubular necrosis
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