Grand Journal of Urology
E-ISSN : 2757-7163

Current Issue
Dear colleagues, I am honored to share with you the third issue of 2023 (volume 3, issue 3) of the Grand Journal of Urology (Grand J Urol) with the contributions of many respected researchers and authors. Grand Journal of Urology (GJU) aims to carry written and visual scientific urology studies to academic platforms and to make significant contributions to the science of urology. Our journal has been abstracted/indexed in Tubitak Ulakbim TR Index, DOAJ, EBSCOhost, J-Gate, Index Copernicus International, EuroPub, SciLit, ResearchGate, ScienceGate and Google Scholar international databases. As of these achievements, the Grand Journal of Urology (GJU) has taken its place among the journals indexed by national and international databases. In this issue of our journal, there are many valuable articles under the subheadings of General Urology, Neurourology, Urolithiasis and Urological Oncology. I hope that these carefully prepared articles will make important contributions to valuable readers, researchers and the urology literature. On this occasion, I would like to express my heartfelt gratitude to our authors who have contributed to our journal with their articles, to our reviewers who have meticulously evaluate the articles. Respectfully yours January 2024 Assoc. Prof. Ekrem GUNER, MD Editor-in-Chief
Original Article
General Urology, Online First: 29 September 2023
Grand J Urol 2024;4(1):001-005, DOI: 10.5505/GJU.2024.28290
Objective: To compare traditional and hybrid model of education in urology among 4th-year medical students in terms of training success Materials and Methods: In our urology clinic, the training success scores of seven randomly selected training groups, who were trained with the traditional model between 1998-2018, and the 4th year medical students who were trained with the hybrid model between 2018-2020 and constituted five randomly selected training groups were compared. Of the total 582 medical students, included in the study, 278 (47.8%) were enrolled in the traditional model group, and 304 (52.2%) in the hybrid model group. The training was evaluated with hands-on applications and theoretical and oral exams. Differences between both male and female students and differences that may vary depending on different faculty members teaching the students were evaluated using multivariate logistic regression analysis. Results: The training success rates were significantly higher in the hybrid model group (300/304; 98.7%) than in the traditional model group (261/278; 93.9%) [p:0.002]. Multivariate logistic regression analysis found that factors such as the number of training groups, gender of medical students, and evaluations of different faculty members did not affect the educational success rate. Conclusion: The hybrid model could be accepted as a mobile education model in a sense. The exam results of medical students educated with the hybrid model were better than those receiviing training with the traditional model which can be explained by the increased accessibility of medical students to education in the hybrid model without constraints of time and place. Additionally, it is thought that conducting the oral exam as a "structured oral exam" also contributed to these results.
Neurourology, Online First: 02 October 2023
Grand J Urol 2024;4(1):006-011, DOI: 10.5505/GJU.2024.61587
Objective: In this study, we aimed to investigate whether there would be any improvement in symptoms of overactive bladder (OAB) after migraine prophylaxis in patients with chronic migraine (CM) and OAB. Materials and Methods: The study group consisted of women aged 19 to 64 years diagnosed as CM according to current International Headache Society (IHS) criteria, and OAB using the OAB-V8 (Overactive Bladder Inquiry Form - V8) and ICIQ-SF (International Consultation on Incontinence Questionnaire Short Form) forms as well as clinical evaluation in the neurology and urology clinics. 63 patients informed and agreed to enter the study were started migraine prophylaxis and evaluated after 6 months for comparison of pre-treatment and post-treatment VPS (visual pain scale), OAB-V8, and the ICIQ-SF scores. Flunarizine, topiramate, venlafaxine and propranolol were used in the treatment of patients. Results: The mean age of 63 women included in the study was 39.15 ± 8.74 (19-64) years. The mean Body Mass Index (BMI) of the patients was determined as 25.41 ± 3.64 (16.4-35.6) kg/m2. After migraine prophylaxis, VPS, OAB-V8 and ICIQ-SF scores decreased significantly in the entire patient group (p
General Urology, Online First: 06 November 2023
Grand J Urol 2024;4(1):012-018, DOI: 10.5505/GJU.2024.07078
Objective: We aimed to investigate the activity of diosmin-hesperidin (DAFLON®) in ischemia-reperfusion injury in the rat kidney. Materials and Methods: Twenty-four Wistar rats were used for the experimental study. Each group comprised of 8 subjects. Sham group (Group 1) was nephrectomized for histopathologic examination and blood samples were obtained for biochemical analysis. Control group (Group 2) was subjected to ischemia for 1 hour and reperfusion for 24 hours, then they were nephrectomized for histopathologic examination and blood samples were taken for biochemical analysis. Treatment group (Group 3) was given 80 mg/kg diosminhesperidin combination (DAFLON®) for 10 days and subjected to ischemia for 1-hour and reperfusion for 24 hours, then they were nephrectomized for histopathologic examination and blood samples were obtained for biochemical analysis. Results: As a result of biochemical analysis and histopathologic examination, more significant results were acquired in regard to other groups. Serum urea values were statistically significant (p
Urolithiasis, Online First: 23 December 2023
Grand J Urol 2024;4(1):019-024, DOI: 10.5505/GJU.2024.38257
Objective: This study aimed to investigate the effect of stone density on the success of ureterorenoscopy (URS) and retrograde intrarenal surgery (RIRS). Materials and Methods: The data of patients who underwent URS or RIRS due to kidney and ureteral stones between January 2013 and March 2018 were retrospectively screened. For all patients, age, gender, comorbidities, the American Society of Anesthesiologists (ASA) score, the presence of preoperative double-J (DJ) stents, extracorporeal shock wave lithotripsy (ESWL) history, ipsilateral stone surgery history, the presence of renal anomalies, stone laterality, stone opacity, stone density, stone size, stone volume, operative time, stone-free status, and the presence and size of residual stones were recorded. Results: The study included 566 patients who underwent URS or RIRS, including 186 women (32.9%) and 380 (67.1%) men. The mean age of the patients was 47 years. The mean stone size was 10 mm, and the mean stone density was 886 Hounsfield units. The mean stone volume was 426.13 mm3. The mean operative time was 31 minutes. The stone-free rate was 89.4%. Stone density, stone size, and stone volume were positively correlated with operative time (p
Case Report
Urological Oncology, Online First: 02 January 2024
Grand J Urol 2024;4(1):025-027, DOI: 10.5505/GJU.2024.02418
Nephroblastoma (Wilms Tumor / WT) is the rare but the most common primary kidney tumor in children. The WT is generally diagnosed between 1 and 5 and the most common diagnosis is the age of 3. Up to 95% of WTs are diagnosed correctly with visualization (ultrasound, computed tomography and magnetic resonance). Histopathologicaly tissue examination is implemented and subtypes are determined. Surgery is one of the key factors in WT treatment. Transperitoneal radical nephrectomy is the standard operation for unilateral WTs. Nephron sparing surgery (partial nephrectomy) is suggested only in selected cases with a single kidney or bilateral WT. Other treatment combination for Wilms tumor involves chemotherapy and radiation treatment. A patient who was diagnosed with Wilms tumor in the right kidney and underwent partial nephrectomy which is rarely implemented or recommended in selected cases is represented in this article.
Urological Oncology, Online First: 12 January 2024
Grand J Urol 2024;4(1):028-031, DOI: 10.5505/GJU.2024.51523
Chest wall malignancies are rare, constituting only 1% of all cancers. Prostate cancer, the second most common in men, typically metastasizes to bones, lymph nodes, and organs. However, sternum involvement is exceptionally rare, particularly with osteolytic metastasis. We report a 75-year-old man, clinically presenting with large anterior chest wall mass, which on further investigation revealed an expansile osteolytic sternal body metastasis from prostate cancer. This rarity poses diagnostic and therapeutic challenges, as documented cases of osteolytic secondaries to the sternum are scarce in medical literature. Diagnostic efforts involved comprehensive imaging and biopsy, confirming prostate cancer metastasis. Management requires a multidisciplinary approach, balancing effective cancer control with preserving the patient"s quality of life through systemic therapies, radiation, and surgery. The scarcity of osteolytic sternal body metastasis in reported cases highlights the atypical pattern of metastasis in prostate cancer emphasizing the need for a deeper understanding and contributing to the knowledge of this uncommon manifestation.
Urological Oncology, Online First: 15 January 2024
Grand J Urol 2024;4(1):032-034, DOI: 10.5505/GJU.2024.73745
Amyloidosis is related to the extracellular deposition of abnormal protein fibrils in various tissues. It is clinically interesting that such cases" clinical, radiological, and even endoscopic presentation mimic urothelial carcinoma to a great extent. Here, we discuss a case of a 34-year-old gentleman who presented with frank painless hematuria. The patient was diagnosed with a bladder mass suspicious of malignancy depending on the clinical presentation aided by the cystoscopic and radiological evaluation. Histopathologic samples of the transurethral resection of the mass proved to be primary bladder amyloidosis. Further investigations of systemic illness excluded the secondary amyloidosis. The purpose of this case presentation is to create awareness among the urologists to think for the rare entity of urinary amyloidosis especially if the histopathology is negative for the malignant cells.